Adobe Encore CS6 Audio Out

I'm using Encore on a DVD project (macOS Sierra 10.12.6) and as you know Encore can playback the timeline and preview your DVD, but for some reason I got no sound output through my brand new 24bit 48k audio interface.

In Encore, one sets the Preference/Audio/Video Out by clicking on Audio Output Device. This will open the Mac Audio Midi Setup. Click on Adobe Encore DVD 6.0 an you will see that all the devices are greyed out. Clicking and selecting your favorite device only activates it briefly, as soon as you return to Encore, all devices turn back to inactive...

Unlike Premiere Pro 6.0, it does not stick. Well the trick is to leave Adobe Encore DVD 6.0 alone, select your Audio interface/device as the System Sound Output in Mac Preferences, and in Audio Midi Setup set the device to 16bit., 24bit does not work with Encore, only 16bit.

At last! Audio output from Encore! 

ProTools Playback Engine, ProTools Aggregate I/O "forgets" Inputs/outputs when disconnecting/re-connecting audio interface

This is happening all too often and it's driving me a bit nuts: when disconnecting and re-connecting the audio interface (same device, native to macOs Sierra) onto my Mac, ProTools Aggregate in the Audio Devices of the Midi Setup goes south.

The output/input gets duplicated and ProTools Aggregate gets confused, acting as if there is no device. On launching ProTools, cahoots ensues:

Duh!

In the picture below, the PT Aggregate I/O is configured normally, and everything works.

Now if I move the computer to another job location, by necessity disconnecting and re-connecting the audio interface, often there is a DUPLICATE and GREYED OUT input/output that ProTools Aggregate I/O is stubbornly set onto. Like an invisible, non-existent device. Hence it produces the Playback engine message above.

I wonder why this behavior? Is it PT? Is it Audio/Midi Setup? Is it the Mac? Anyone of you having this problem on your setup and can share some light?